I have some on back order just for fun. Their 325's work well for me, and Hodgdon posts tested loads for H110. Does anyone have experience to share with heavy bullets like this? Ruger Blackhawk, of course.
I shoot 340s in my Ruger Bisley, and for a lighter but still powerful load I use 10 gr. of Longshot with a standard primer for about 850 fps. For an extra couple hundred feet per second, I use the same bullet and 20 gr. of 4227.