OK, I see your issue, and I don't know if this bullet is your bullet, but the Hornady 7th edition lists this...
255gr #12458 FP Cowboy
B.C.: 0.117 C.O.L. : 1.575"
Their test gun was a Ruger Bisley 7.5" and out of a dozen powders listed only two got to 900fps at listed max. The rest of them listed 850fps at max, except , of course, Trail Boss, which went only 750fps at max.
Personally, I consider these loads overly conservative, but that's just me.
Max for Unique they listed was 7.0gr @ 850fps.
Now, the picture in the Hornady book shows what looks to me like a swaged bullet, which is probably rather soft, which might be the reason for the conservative load maximums.
An old Lyman manual lists 7.5gr Unique as the factory duplication load with a 250gr bullet. 8.5gr is a load that has been used for generations in Colts and is quite safe in any modern .45 Colt firearm.