Mid-frame Ruger SAs (New Vaquero and the flat-top Blackhawks in 357Mag, 44Spl and 45LC/ACP) have had a new cylinder boring system done at Ruger since their re-introduction in 2004. In the new system all the chambers are drilled and cut with the same bits/reamers in sequence, so the uniformity of the chambers has gone way up as has average accuracy. The old system had all six chambers reamed at once with six bit/reamer sets all going at once, and they weren't always uniform.
This process was applied to the large-frame series in 2007 and can be identified (with one exception) by the "lawyer's warning billboard" on the barrel: if it is under the barrel it had the new cylinder making process, side-barrel means the old process. The exception is the 2006 Blackhawk Flattop 50th Anniversary 44Magnum, the one NOT marked "Super". This had a side-barrel warning label at least in the initial run, but all of them have the new-type improved cylinder.
At some point the principle got applied to the small-frame Single Six. I don't know when, but it explains how they were able to do 9-shot .22Magnum and 10-shot 22LR varieties.