At the range today, after I shot up all the 45/70s I had loaded to try in my Sharps, I primed some cases and filled them to the top with Swiss 3f. I got a card wad in there to hold the powder in and then breech seated a 550 grain bullet. I weighed a charge later and it weighed out at 81 grains. I shot 10 of those and they did kick, some. My regular 45/70 loads are pretty pleasant to shoot, those 10 were at the upper end of pleasant, and if I had to touch off 90 or 100 grains of powder behind a big bullet like that, I'm almost certain I would find life kinda grim after the first 5 shot string.
I'd still LOVE a 45/110.
Steve