It would have to be an LSR (Light Service Revolver), a medium frame wheel gun using the advanced materials, design, and assembly techniques pioneered with the LCR.
I would love to see the LSR offered in the following configurations:
10-shot .22 LR
9-shot .22 Magnum
8-shot .327 .32
6 or 7-shot .357 /.38
5-shot .44 Special
for the semi-auto crowd:
8-shot .32 ACP
7-shot .380
7-shot 9mm
6-shot 10mm
5-shot .45 ACP
Are you listening Ruger?