My Pietta .44 Remington is more accurate than my Uberti Colt .36. I don't believe it has a thing to do with the size of the hole in the barrel, though. It's just that my .44 happens to be a more accurate pistol than my .36. ( Or any of the other 9 centerfire pistols I own either, as far as that goes.)
I agree with Willy and Fur that the .44 is easier to load and, in my state, is also the only one of the two legal for deer hunting.
Steve