You've made a very sound defense choice, although if you shoot much of that lead Plus P .38 ammo, you may have a job cleaning out your bore. Standard lead SWC's willl suffice for target work, tin cans, and small game up to roughly jackrabbit size.
Remington makes a medium-velocity .357 round with a 125-grain bullet. Got a brass jacket as I recall, but it seems to cause no problems. Gives about 1220 nominal muzzle velocity, and Marshall and Sanow claim 83% one-shot stops in their shooting studies. For defense on large animals or to shoot into cars I'd step up to a 158-grain bullet. I like Federal's Hydra-Shok, and several people on the forums and a Fed factory rep tell me it's a great deer round, within the range limits of the .357. Remington's 158 JHP is also good. Use softpoints if you need more penetration, as maybe with bears. If you just fire this ammo occasionally, to be sure you know how it feels and where it shoots, then carry it for business, wear won't be much of a factor.
Avoid the hot 125 and 110 grain magnum ammo. Eats up barrel throats and sometimes cracks them, cuts the top strap at the barrel juncture and generally wears the gun.
Keep in mind that the Combat Magnum (Models 19 and 66) was designed to be basically a .38 that could be used with .357's when use of that ammo was appropriate. It was never intended to be used full time with magnums in routine practice. I got this directly from Bill Jordan, whose concept the gun was. The gun lasts very well if not hotrodded all the time. Its handling qualities and ability to use .357 ammo when warranted make it a superb all-round revolver. Many see it as the ideal gun for someone who can or will have only one. If you want to fire many magnums, get a M686, an N-frame (Models 27 and 28) or a Ruger GP-100. Really, one should have both a primary .357 and a Combat Magnum for when convenience outweighs longterm endurance with full loads.
Lone Star