I wouldn't get too hung up on velocity with either bullet (not sure what an FXP bullet is). The single biggest thing about using the .357mag on deer is that they shed velocity quickly and the bullet you use will be effected by this to quite an extent. I've shot deer with the .357mag and the distance makes a huge difference more in expansion than it does in penetration. Any decent mag load will give you all the penetration you need on a deer. I've shot one deer at around 90 yards with a 158g Hornady XTP and then shot the same deer at 35 yards after it ran towards me. Both hits were broadside and each one hit one rib going in and both stopped on the off side under the hide. One bullet had very little expansion and one expanded quite a bit. Both bullets stopped under the far side hide. I've recovered a lot of bullets from deer over the years that have been shot with the .357mag (I've shot over fifty with this caliber in a handgun alone). For a compromise between expansion and penetration I strongly suggest using the 158g XTP as a first choice and the 180g as the second choice. The 180g just doesn't expand as well as the 158g out of a handgun. FWIW, I've shot a few with a TC Contender in .357mag also. I've never lost even one deer with the .357mag and I attribute that to bullet placement rather than velocity or penetration. Using a handgun in this caliber will require you to have the right shot placement regardless of velocity or penetration. It's the most important factor of all. Good luck.