That is a big difference but does the manual specify regular or magnum primers? Also the manual loads were probably developed with a test barrel unless otherwise stated. Maybe much longer than your revolver barrel. You need to post more specifics I guess. Also you might see notable differences from one gun to the next with the same barrel length due to bore size, cylinder throat diameters, etc. but not that much diff. Try the handloading forum instead of the general handgun, maybe.