I agree with Stephen until he gets to the part of hearing protection. Definetly would not go without it at the range or when practicing, but when it comes to home defense, that would be on the bottom of my list of priorities. I don't believe I will be worrying about hearing protection before having to shoot an intruder. I've been a State Trooper for awhile and hearing protection is not normally worn while patrolling. However, he does make a good point on over penetration. A .357 mag with a 125 gr bullet would be one of the ultimate manstoppers. Thats the gun and bullet weight used by LE for yrs and is still being used. But when it comes to home defense, you need something that works well for quick, reactions shots more than something your going to be sitting there aiming at for awhile. I think if you talk to just about everyone in LE, there going to tell you there first choice would be the shotgun. If you have a chance to grab the shotgun, you do. You use your side arm if you don't have time to gun to the Shotgun. I would go for a shorter barrel pump shotgun, probably with #4 shot. You get into the buckshot or slugs, your getting back to the over penetration. Also, hearing that shotgun rack will probably get most burglars turning tail without having to fire around. If thats out of the question and your going to stick the the .357, I would go with a hollow point designed to expand rapidly. My duty weapon is a .357 sig with 125 gr speer gold dot hollow points. There designed to expand rapidly and not penetrate all the way through. The ballistics to a .357 sig and a .357 mag or nearly identical. I saw a man that was smaller in size that an officer shot 5 times at close range (under 10 yrds). He was carrying 125 gr gold dot and all 5 penetrated through, but they did leave exit holes the size of your fist. If you have a choice, go with the shotgun.