I had the same question. Looks like the 180 is winning hands down. I'm looking for deer only, and the 300 WSM is a little overkill, in my opinion. I bought it when my wife took over my 270 A bolt, and I thought that I could use it for Moose, Elk or what ever. I can see bigger game - bigger bullets, but for deer? What is the advantages of lighter and heavier? Lighter means faster, less drop. Heavier less wind affect and more penitration. Lighter bullet less recoil right? Do heavier bullets shoot more accurate? Then I wouldn't have to rework a load if I ever do get the $ for Elk or moose......... Seems like I'm talking myself into 180's. Any thing else? Any opinions welcome!!