CAUTION: The following post includes loading data not covered by currently published sources of tested data for this cartridge. USE AT YOUR OWN RISK. Neither the writer, The Firing Line, nor the staff of TFL assumes any liability for any damage or injury resulting from the use of this information.
I use H110 in my subsonic .300 Blk loads, which use 194-220 gr bullets (including the 208 gr AMax).
I stopped using reloading data for new bullets.
I just go straight to 9.3 to 9.5 grains.
If I'm fairly certain that it'll be in the velocity range that I want, I may load a whole box.
If the bullet is different enough (like the 194 Lehigh ME) that I expect to be tweaking the load, I might only load 10-20 for testing.
I chronograph and 'ear' test for cracking, and go from there. Once, I had to back down from 9.5 to 9.3 gr (hence why I sometimes start at 9.3 now). And, a couple of times, I had to bump it up closer to 10 gr. But, in most cases, I was between 1,000 and 1,050 fps - which is perfectly acceptable to me.
If you go look at 190-240 gr load data, you'll find that the vast majority of loads using H110 are running 9.3 to 10.5 gr and they're never even remotely close to standard pressure, let alone max.