As a money matter, I used a .270 for whitetail hunting from 1963 until around 1970. From 1970 on, I've mostly used a .30-'06 and to a lesser extent a .243.
From the standpoint of recoil, a 130-grain bullet in the .270 isn't that much less than my standard 150-grain in the '06. Roughly 13% reduction?
The vast majority of all hunting shots are taken within 200 yards.
As a generality, all non-magnums from the .243 through the '06, if two inches high at 100 yards, will be
about dead on at 200 yards and
about six inches low at 300 yards.
And, roughly 20 to 24 inches low at 400, and around four feet low at 500 yards. 98% of all hunters can't tell the difference between 300 and 500 yards without a range finder, IMO.
I'm a long-time handloader, so I go with the '06 because of its versatility. And the cartridge, itself, with factory ammo is pretty doggoned versatile, as well.
, Art