I've personally never heard of anyone loading that heavy of a bullet in a .357 Magnum. I have heard of 220 gr. loads in the .357 Maximum, but thats a different proposition all together.
The heaviest bullet I could find any loads for in my many reloading texts was for a 200 gr. bullet. 14.5 grs. H-110= 1392 fps, 12.0 grs. 2400=1336 fps, 13.2 grs. IMR 4227=1222 fps. These are all max loads, so if you try them start a couple grs. lighter.
The 250 gr. bullets are all made for .358 rifle cartridges, ie. .35 Whelen, .358 Win. etc., as far as I know. Personally, I wouldn't use anything heavier than 180 grs. in a .357. If you need more power than that, something like a .41 or .44 Mag would probably better serve you.
Hope this helps.