I just looked at a ballistics/trajectory table for this round. For the 117 grain bullet (which was the only cartridge shown listed for this rifle) the trajectory table inicated that this round hits 4.3 inches high at 100 yards and a fraction over 19 inches low at 300 yards. These results were probably achieved with a 24" barrel. By modern day standards, that's a pretty curved trajectory and if your barrel is shorter than 24", your actual trajectory will probably be even more curved, but maybe this will give you a general idea. Anyway, if you've zeroed this rifle in for say, 100 yards, but are shooting at a treed cougar from 50 feet away, you probably need to aim about 6 or 7 inches low with this round in order for it to hit the cat exactly where you want to hit him. But don't take my word for it, what do I know? I'm a credit manager reading a trajectory table. I've never even seen a cougar in the wild. So my advice is this: Since a 50' shot is apparently the rule, and not the exception in this type of hunting, I'd try at least one 50' shot on a paper target beforehand to see exactly where it printed in relation to my aiming point. Then once I had a treed cougar, I'd use the old "Tennesse" elevation technique (i.e., aim where-ever I had to aim to make my bullet hit exactly where I wanted it to hit) to take out take out that cat. Knowing exactly where your bullet will hit at 50" is likely very important in this type of hunting because 50' is probably no distance at all for a scared, hurt, angry cougar to travel in the blink of an eye. A wounded but basically still fully functional cat might be on you almost before you knew it.