The 4895 "WILL" get you a decent load but will also leave some room in the case. While it isn't the best option, it has shown very good results with accuracy, and decent enough velocity for hunting with.
I used IMR-4831 with the 100gr Nosler's when I started out with the 25, but I found them a bit explosive, and they tended to drift a bit more in the wind than the heavier weights. The Partition however did account for several deer in the freezer.
As mentioned however, if your looking for top end results with the 100gr loads, IMR or H-4350 will suit you better. IMR-4350 was the powder reccomended by Sierra with their 100gr bullet at around 52grs.
For anything 110grs and up it is VERY hard to beat out RL-22. Our standard load for our 25 uses the 115gr Partiton over 56'ish grains of RL-22 for 3150fps from my stock Rem 700. It shoots awesome at around 3/4" at 200yds, and really puts the smackdown on deer or hogs.