you will probably have a lot of misfires because the 22 lr rim is thinner than a magnum rim and the fring pin might not reach the rim. as mentioned before the case will probably split if it does go off
I have a S&W model 51 in 22mag that my little boy was wanting to shoot, and I didn't have any ammo but 22Lr. I'll what till i get some. Thanks for the info.