Rifletom, interesting that you got better accuracy with IMR4064. I may give it a try in my rifle when I run out of Varget.
I haven't spent much time loading the .22-250 at all. I started with H380 but gave that up because hunting in the winter using H380 I noticed POI kept changing. After that I tried Varget, it gave good performance and was accurate in my rifle. But, recently I've been thinking of trying a different powder to see if there is something better.
Also wish I could find another bullet as the best so far has been the Sierra 52 gr MK. I'd like to find a 55 gr bullet that gives the same accuracy.