No experience with Unique, sorry, and I won't quote load books at you since the load books are't doing the load work-up or shooting the handgun...
There are TONS of load work-up articles around,
You are already on the right track.
The only bit of advise I can add,
If you have to beat yourself or the firearm up to get expansion, try a different powder/bullet when these are gone,
If it isn't comfortable for you AND the firearm, then it becomes a chore to practice & you will practice/shoot less.
Common sense, I know, but we sometimes get locked into things with tunnel vision and forget the basics...
Hornady XTP in 124 grain, I use them them all the time, my favorite all around hollow point. You will probably be happy with them in 'Warm' to 'Medium Hot' velocities, not great expansion with short barrels/slower velocity.
They expand fine at velocities other 'Super Duper Self Defense' won't begin to expand.
If it's a 'Holster' and not 'Pocket' handgun, they will probably work.